Orthopedics & Pain Management

Orthropic

Orthrophic therapies include subchondral and intraosseous injections, primarily indicated for patients with more advanced osteoarthritis, particularly in the knee and hip. By targeting the underlying bone and joint environment, this approach aims to improve joint integrity, reduce pain, and support structural stability.

Eligibility Framing

Focused on joint function and longevity

Eligibility for Orthrophic therapies is determined through a thorough clinical evaluation, including imaging and functional assessments of the affected joints. These evaluations allow our medical team to assess the severity of osteoarthritis, structural integrity, and suitability for subchondral or intraosseous injections. Each patient is considered individually to ensure a personalized protocol that maximizes safety, efficacy, and long-term joint support.

Check Eligibility

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Who may benefit
Orthrophic therapies are ideal for patients with advanced osteoarthritis, particularly in the knee or hip, who are seeking to reduce pain and improve mobility. They may also benefit individuals with structural joint concerns, chronic discomfort, or limited response to conventional treatments, as well as those aiming to delay or avoid joint replacement surgery.
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What it supports
This advanced joint regeneration approach supports the health and integrity of the underlying bone and joint environment. It is designed to reduce pain, enhance structural stability, improve function, and promote the body’s natural repair processes. By addressing the root causes of degeneration, Orthrophic therapy helps restore joint performance and long-term mobility.
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Safety, oversight and responsibility
Orthrophic treatments are performed under strict clinical supervision by an experienced medical team. Each protocol is carefully planned, monitored, and adjusted based on individual patient response to ensure safety and optimal outcomes. Our approach adheres to the highest standards of care, prioritizing responsible clinical practice, evidence-based methods, and long-term joint health.
RMI APPROACH

A sequenced biological protocol

The 3-Step
Regenerative Protocol - A physician-guided, multi-day clinical process designed to reduce inflammatory burden and support the body’s regenerative signaling.

1

Plasma exchange

After medical consultation and bloodwork, patients arrive for intake and vitals. Therapeutic Plasma Exchange (TPE) removes inflammatory substances. Duration: 2–3 hours.

2

Clinical review & program design

Every patient begins with a physician-led review of medical history, labs, and goals. This consultation helps determine suitability and allows the care team to tailor the protocol to individual needs.

3

Cellular infusion

Autologous cells are administered intravenously. This sequence primes the biological terrain for optimal cell health. Nutritional IV included.

RMI EXPERIENCE

Designed for clarity, privacy and continuity

The RMI Experience: "Safety, Science, and You" – Every stage of your journey combines advanced regenerative medicine with a destination experience, private coordination, thoughtful surroundings and structured follow-up that make complex treatment feel clear, contained and purposeful.

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Eligibilty Review

A detailed consultation to understand your health history, clarify expectations and define realistic, long‑term goals for treatment and recovery.

Medical Onboarding

You meet with an RMI physician to review your needs, confirm eligibility and determine any testing required before treatment.

Treatment & Care

Within our state-of-the-art facility, regenerative therapies are delivered by experienced physicians in a quiet, closely supervised setting.

Privacy & Trust

Every interaction, consultation, and record is handled with care, ensuring that your data remains private and protected.

Concierge Experience

Everything around your stay is privately coordinated with the medical team, so your energy goes toward preparation, treatment, and recovery.

Ongoing Guidance

Scheduled check‑ins and virtual consultations keep your progress on track and your mind at ease, following your departure.

TESTIMONIALS

“I first heard about this type of therapy a few years ago and did my research. I spoke to Mike Smith — one of the greatest jockeys of all time — and he swears by it. That meant something to me. When the time felt right, I didn’t hesitate. I got on a plane and came straight here to RMI.”

The only jockey to win the Arc de Triomphe, Breeders’ Cup Classic, King George, Dubai World Cup, and JapanCup; he claimed three British jockey championships (1994, 1995,2004) and over 3,300 victories, including 77 at Royal Ascot.​

Frank Dettori

The experience I received at RMI worked an absolute dream. They didn’t just manage my pain; they actually helped my body repair itself. They are the reason I’m going to be back on the mats and back where I left off far sooner than anyone expected.

Known as “The Hitman,” is a legendary British Muay Thai fighter with over 100 professional fights, 48 knockouts, and 9 world titles.​

Liam Harrison

“RMI stands out to me for two reasons: they’re operating at the cutting edge of what’s currently possible with regenerative medicine, and they’re backed by some of the most experienced and trustworthy longevity physicians in the world.”

Dave Asprey is renowned as the founder of Bulletproof Coffee and a pioneer in biohacking. Four times NYT

Dave Asprey

“What I appreciate about RMI is that it aligns with how I think about health
professionally: proactive, science-driven, individualized, and focused on the long game. I’m not here for a quick fix. I’m here because I want to be functional, clear-headed, and capable for as long as possible. That’s what good medicine should be working toward — and that’s what I’ve found here.”

Chief Population Health Officer at Vail Health and Executive Director of Eagle Valley Behavioral Health

Chris Lindley

“I came to RMI and gave it a shot. A few weeks later, I felt brand new. That’s not
something I say lightly — I don’t really believe in much — but what happened here was
real. I woke up feeling well-rested, like a different person.”

UFC Heavyweight World Champion 2012​

Derrick Lewis

“I’ve referred astronauts here. Several have come through, and every one of them has had
a positive experience. I’ve also gone through a number of their therapies personally,
which is why my trust in this team isn’t just professional — it’s personal. I wouldn’t send
my astronauts somewhere I hadn’t vetted myself.”

NASA flight surgeon for 25 year and head of NASA’s Fatigue Management, Human Health, Performance, and Longevity programs, as well as medical director of Aerospace and Occupational Medicine clinics

Smith Johnston

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DISCLAIMER – RMI Health is a longevity and regenerative medicine clinic that provides advanced, medically supervised stem cell and related therapies under license from the Costa Rican Ministry of Health. All treatments are subject to eligibility criteria and are only recommended after a full clinical review by qualified physicians, which may include medical history, diagnostic testing, and consultation with your existing care team. Outcomes vary between individuals and depend on many factors—including diagnosis, overall health, and adherence to medical guidance—so no specific result, degree of improvement, or duration of benefit can be promised or guaranteed. As with any medical procedure, regenerative and stem cell therapies carry potential risks, side effects, and limitations, which will be discussed with you in advance to support informed decision‑making; RMI encourages patients to seek independent medical advice when needed and to consult insurers regarding coverage, as many longevity and regenerative treatments may be considered elective or investigational.​

THIS NOTICE MUST BE PROVIDED TO YOU UNDER FLORIDA LAW – This centre performs one or more stem cell therapies that have not yet been approved by the United States Food and Drug Administration. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy.

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